A new report published in the Journal of Trace Elements in Medicine and Biology raises a disturbing possibility: that aluminum hydroxide, the dominant metal-based adjuvant used in vaccines today, is causing aluminum overload at injection sites, and contributing to the pathogenesis of diseases such as chronic fatigue syndrome, macrophagic myofasciitis and subcutaneous pseudolymphoma.
Discussed is the case of a 45-year old woman with vaccine-induced subcutaneous pseudolymphoma, a type of skin lesion characterized by collections of lymphocytes, macrophages, and dendritic cells in the skin. The researchers performed a skin biopsy at the injection site and found aluminum (AI) deposits in her macrophages. When the skin sample was assayed for AI and quantified, it was found to contain 768.1 micrograms per gram, dry weight, versus 5.61 and 9.13 in two control patients – up to 153-fold higher concentrations.
The report cautioned: “Given the pathology of this patient and the high Al concentration in skin biopsy, the authors wish to draw attention when using the Al salts known to be particularly effective as adjuvants in single or repeated vaccinations. The possible release of Al may induce other pathologies ascribed to the well-known toxicity of this metal.”
As referenced, aluminum-based (and other) vaccine adjuvants are “effective” at increasing antibody titers, but they perform this feat through the hypersensitization and/or dysregulation of the humoral pole of the immune system (Th2), which is the immunological equivalent of kicking a beehive.
While intrinsically toxic adjuvants enable manufacturers to produce more antibodies with less antigen (often a profit-motivated decision), these synthetically-generated increases in the sheer number of antibodies produced does not in any way guarantee they will target the correct antigen (i.e. antibody-antigen affinity), which is the true measure of vaccine effectiveness; in fact, these unnaturally stimulated antibodies cross-react with and/or attack self-structures, e.g. myelin basic protein, leading to the break down of immunological self-tolerance, i.e. autoimmunity.
It is a curious fact of vaccine history that while aluminum hydroxide has been injected into billions of people and has been used for almost one century as the only vaccine adjuvant approved worldwide, its mechanism of action is not fully understood, and is only being investigated with any depth in the past five years.
We know that one way in which aluminum hydroxide induces an enhanced immune response is through activating the inflammasome within myeloid cells, a key immune-mediated activator of the inflammatory response and which is known to induce cell death. And yet, without understanding its exact mechanism of action, it is impossible by principle to ascertain fully its risk to health.